Dr. Kenzou Tenma, an elite neurosurgeon recently engaged to his hospital director's daughter, is well on his way to ascending the hospital hierarchy. That is until one night, a seemingly small event changes Dr. Tenma's life forever. While preparing to perform surgery on someone, he gets a call from the hospital director telling him to switch patients and instead perform life-saving brain surgery on a famous performer. His fellow doctors, fiancée, and the hospital director applaud his accomplishment; but because of the switch, a poor immigrant worker is dead, causing Dr. Tenma to have a crisis of conscience. So when a similar situation arises, Dr. Tenma stands his ground and chooses to perform surgery on the young boy Johan Liebert instead of the town's mayor. Unfortunately, this choice leads to serious ramifications for Dr. Tenma—losing his social standing being one of them. However, with the mysterious death of the director and two other doctors, Dr. Tenma's position is restored. With no evidence to convict him, he is released and goes on to attain the position of hospital director. Nine years later when Dr. Tenma saves the life of a criminal, his past comes back to haunt him—once again, he comes face to face with the monster he operated on. He must now embark on a quest of pursuit to make amends for the havoc spread by the one he saved. [Written by MAL Rewrite]

"Mushi": the most basic forms of life in the world. They exist without any goals or purposes aside from simply "being." They are beyond the shackles of the words "good" and "evil." Mushi can exist in countless forms and are capable of mimicking things from the natural world such as plants, diseases, and even phenomena like rainbows. This is, however, just a vague definition of these entities that inhabit the vibrant world of Mushishi, as to even call them a form of life would be an oversimplification. Detailed information on Mushi is scarce because the majority of humans are unaware of their existence. So what are Mushi and why do they exist? This is the question that a "Mushishi," Ginko, ponders constantly. Mushishi are those who research Mushi in hopes of understanding their place in the world's hierarchy of life. Ginko chases rumors of occurrences that could be tied to Mushi, all for the sake of finding an answer. It could, after all, lead to the meaning of life itself. [Written by MAL Rewrite]

Following an encounter with oddity specialist Izuko Gaen, third-year high school student Koyomi Araragi wakes up in a strange, deserted void only to be greeted by a joyfully familiar face in an alarmingly unfamiliar place. Araragi, with the help of his girlfriend Hitagi Senjougahara, maneuvers through the webs of his past and the perplexities of the present in search of answers. However, fate once again delivers him to the eccentric transfer student Ougi Oshino, who brings forth an unexpected proposal that may unearth the very foundation to which he is anchored. As Araragi peels back the layers of mystery surrounding an apparition, he discovers a truth not meant to be revealed. [Written by MAL Rewrite]

In 1972, a popular student in Yomiyama North Middle School's class 3-3 named Misaki passed away during the school year. Since then, the town of Yomiyama has been shrouded by a fearful atmosphere, from the dark secrets hidden deep within. Twenty-six years later, 15-year-old Kouichi Sakakibara transfers into class 3-3 of Yomiyama North and soon after discovers that a strange, gloomy mood seems to hang over all the students. He also finds himself drawn to the mysterious, eyepatch-wearing student Mei Misaki; however, the rest of the class and the teachers seem to treat her like she doesn't exist. Paying no heed to warnings from everyone including Mei herself, Kouichi begins to get closer not only to her, but also to the truth behind the gruesome phenomenon plaguing class 3-3 of Yomiyama North. Another follows Kouichi, Mei, and their classmates as they are pulled into the enigma surrounding a series of inevitable, tragic events—but unraveling the horror of Yomiyama may just cost them the ultimate price. [Written by MAL Rewrite]