After a stern yet compelling speech by Otto, Subaru Natsuki solemnly swears that he will successfully make it through this timeline and save everyone he can along the way. The first step toward achieving this goal is to help Emilia work through her past; however, that is easier said than done. Feeling as if she has been lied to by everyone around her, it will be difficult for Emilia to trust anyone, even Subaru, her self-proclaimed knight. Re:Zero kara Hajimeru Isekai Seikatsu 2nd Season Part 2 presents the culmination of Subaru's experiences with the Sanctuary and its people, along with his unwillingness to give up hope on saving them. [Written by MAL Rewrite]

Dr. Kenzou Tenma, an elite neurosurgeon recently engaged to his hospital director's daughter, is well on his way to ascending the hospital hierarchy. That is until one night, a seemingly small event changes Dr. Tenma's life forever. While preparing to perform surgery on someone, he gets a call from the hospital director telling him to switch patients and instead perform life-saving brain surgery on a famous performer. His fellow doctors, fiancée, and the hospital director applaud his accomplishment; but because of the switch, a poor immigrant worker is dead, causing Dr. Tenma to have a crisis of conscience. So when a similar situation arises, Dr. Tenma stands his ground and chooses to perform surgery on the young boy Johan Liebert instead of the town's mayor. Unfortunately, this choice leads to serious ramifications for Dr. Tenma—losing his social standing being one of them. However, with the mysterious death of the director and two other doctors, Dr. Tenma's position is restored. With no evidence to convict him, he is released and goes on to attain the position of hospital director. Nine years later when Dr. Tenma saves the life of a criminal, his past comes back to haunt him—once again, he comes face to face with the monster he operated on. He must now embark on a quest of pursuit to make amends for the havoc spread by the one he saved. [Written by MAL Rewrite]

Fifteen-year-old Megumi Shimizu dreamed of a glamorous life in the big city; however, her unexpected death in the quiet village of Sotoba marks the beginning of what appears to be a ferocious epidemic that turns the hot summer into a season of blood and terror. A young doctor named Toshio Ozaki begins to doubt the nature of the disease and comes to understand that to discover the truth, he must abandon his humanity. Meanwhile, Natsuno Yuuki, an antisocial youth from the city, is haunted by the sudden death of Megumi and must realize the pain of friendship in the face of his own tragedy. Toshio and Natsuno form an unlikely pair as they work together to save Sotoba before it transforms into a ghost town of vampires. Shiki, adapted from the horror novel written by Fuyumi Ono, goes beyond the average vampire story. It tells the tragic tale of survival in a world where one cannot easily distinguish between good and evil. Abandoned by God, the Shiki, as the vampires call themselves, have only their will to live as they clash with the fear of the paranoid/unbelieving villagers. Shiki explores the boundary that separates man from monster. [Written by MAL Rewrite]

A reunion that was supposed to spell the arrival of peaceful times is quickly shattered when Subaru Natsuki and Emilia return to Irlam village. Witnessing the devastation left behind by the calamities known as Sin Archbishops, Subaru sinks into the depths of despair as his ability to redo proves futile. As the group makes their way to the Sanctuary in search of answers, Subaru has an unexpected encounter with the Witch of Greed—Echidna. Subjected to her untamed rhythm, he is forced to dive into the spirals of the past and future. At the same time, several mysterious threats set their sights on the Sanctuary, heralding a horrific fate for the hapless people trapped within. Everlasting contracts, past sins, and unrequited love will clash and submerge into a river of blood in the second season of Re:Zero kara Hajimeru Isekai Seikatsu. Pushed to the brink of hopelessness, how long will Subaru's resolve to save his loved ones last? [Written by MAL Rewrite]